Abscesso intraorbitário e intracraniano por Aspergillus fumigatus

Abscesso intraorbitário e intracraniano por Aspergillus fumigatus


Luís Augusto Rogano,
Oswaldo Tella Jr.,
Italo Suriano,
Fernando Menezes Braga,
Paulo Gois Manso


Arquivos Brasileiros de Oftalmologia

versão impressa ISSN 0004-2749versão On-line ISSN 1678-2925

Arq. Bras. Oftalmol. vol.53 no.2 São Paulo mar./abr. 1990



Aspergillus infections involving the orbit and the CNS is a rare pathology. We present one case of a 12 years old male who suffered a penetrating injuring with a piece of wood at the level of the lower lid. CT scan reveled a hyperdense area with irregular lesion at the medial position of the orbit and invading the supra-se-lar and parasselar region. The patient was submitted to 3 craniotomies and clinically treated with Anfotericin B and Rocefin (Ceftriaxona). A review of the literature was done.


1 AGARWAL, L.P.; MALIK, S.R.K.; MOHAN, M. ET AL - Orbital Aspergillosis. Brit. J. Ophathal., 46:559-62, 1962,
2 AISNER, J.; SCHIMPTT, S.; WIENIK, P. - Treatment of invasive Aspergillosis: Relation of early diagnosis and treatment to response. Ann Internal Medicine, 86:539-43, 1977.
3 BEAL, M.F.; O'CANOLL, C.P.; KLEINMAN, G.M. ET AL - Aspergillosis of the nervous system. Neurology, 32:473-79, 1982.
4 CENTANO, R.S; BENTSON, J.R.; MANCUSO, A.A. - CT scanning in Rhinocerebral Murcomycosis and Aspergillosis. Neurorradiology, 2:383-89, 1981.
5 COCCIA-PORTUGAL, M.A.; SIELING, W.L.; TERBLANCHE, A.P.S. ET AL - Aspergillus brain abscess, SAMJ, 71:116-18, 1987,
6 CORREA, A.J.E.; BRINCKHAUS, R.; KESLER, S. ET AL - Aspergillosis of the fourth ventricle. J. neurosurg., 43:236-38, 1975.
7 FISCHER, B.D.; ARMSTRONG, D.; YU, B. ET AL - Invasive Aspergillosis. The American Journal of Medicine, 71: 571-77, 1981.
8 GALLI, G.; GANDOLFINI, M.; LENZI, A. ET AL - Intraventricular and Intravenous use of Amphotericin B in a case of non-surgical cerebral Aspergillosis. J. Neurosurg. Sci., 27:59-61. 1983.
9 GOLDHAMMER, Y.; SMITH, J.L.; YATES, B.M.; YATES, B.M. - Mycotic Intrasellar Abscess. Am. Journal of Ophat., 78:478-84, 1974.
10 GREEN, W.R.; FONT, R.L.; ZIMMERMAN, L.E. - Aspergillosis of the Orbit. Archives of Opht., 82:302-13, 1969.
11 HEDGES; T.; LEUNG, L.S. - Parasselar and orbital apex syndrome caused by aspergillosis. Neurology, 26: 117-120, 1976.
12 HOOPER, D.C.; PRUITT, A. A.; RUBIN, R. - Central Nervous System infection in the chronically immunosupressed. Medicine, 61(3): 166-84, 1982.
13 KAUFMAN, D,: THAL, L.J.; FARMER, P.M.; Central Nervous System aspergillosis in two young adults. Neurology 26:484-88, 1976.
14 KLEIN, H.J.; RICHITER, H.P.; SCHENMAYR, W. - Intracerebral Aspergillus abscess. Case Report. Neurosurgery, 13(3): 306-9, 1983.
15 LEDERMAN, I.R.; MADGE, G. - Endogenous intraocular Aspergillosis. Arch Opthalm., 76: 233-37, 1966.
16 LUCANTONI, D.; GALZIO; R.; ZENOBI, M. ET AL - Right occipital cerebral abscess caused by Aspergillus fumigatus. J. Neurosurg. Sci.; 31: 29-31, 1987.
17 McCORMICK, W.F.; SCHOCHET, S.S.; WEAVER, P.R. ET AL - Disseminate Aspergillosis. Arch Patol., 99: 353-59, 1985.
18 MOHANDAS, S.; AHUJA, G.K.; SOOD, V.P. ET AL - Aspergillosis of the Central Nervous System. J. of Neurol. Sci., 38: 229-33, 1978.
19 MUKOYAMA, M.; GIMPLE, K.; POSER, C.M. - Aspergillosis of the Central Nervous System. Neurology, 19: 967-74, 1969.
20 PAREDIS, A.J.; ROBERTS, L. - Endogenous Ocular Aspergillosis. Arch. Ophthalm., 69: 125-29, 1963.
21 RIFKIN, B.M.; DUBBER, A.H.C.; GALE, M. ET AL - Aspergilloma of Paranasal Sinues and Orbit in Northesen Sudanese. Lancet, 1: 746-47, 1966.
22 SHAPIRO, K.; TABADDOR, K. - Cerebral Aspergillosis. Surg. Neurol., 4: 465 - 71, 1975.
23 TULLY, R.J.; WATTS, C. - Computed Tomography and Intracranial Aspergillosis. Neurorradiology, 17: 111 - 13, 1979.
24 VEIRS, E.R; DAVIS, T. - Fungus Infection of the Eye and Orbit. Arch. Ophthalm, 59: 172-76, 1958.
25 VISUDHIPAN, P.; BUNYARATANESE, J.S.; KHATANAPHAR, S. - Cerebral Aspergillosis. Report of three cases. J. Neuros., 38: 472-76, 1973.
26 WELLER, W.A.; JOSEPH, D.J.; HORA, J.F. - Deep mycotic involvement of the right maxillary and ethimoid sinuses, the orbit and adjacent structures. The Laringoscope, 70: 999-1016, 1960.
27 YOUNG. R.C.; BENNETT, J.E.; VOGEL, C.L. ET AL - Aspergillosis. The spectrum of the disease in 98 patients. Medicine, 49(2): 147-173, 1970.
Política de Privacidade © Copyright, Todos os direitos reservados.