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Ação dos colírios de timolol a 0,5% e betaxolol a 0,5% sobre a concentração protéica do humor aquoso pela laser "flare" fotometria em olhos normais e com glaucoma crônico simples

Ação dos colírios de timolol a 0,5% e betaxolol a 0,5% sobre a concentração protéica do humor aquoso pela laser "flare" fotometria em olhos normais e com glaucoma crônico simples

Autores:

Mirian Skaf,
Paulo Augusto de Arruda Mello,
Rubens Belfort Jr.

ARTIGO ORIGINAL

Arquivos Brasileiros de Oftalmologia

versão impressa ISSN 0004-2749versão On-line ISSN 1678-2925

Arq. Bras. Oftalmol. vol.58 no.2 São Paulo abr. 1995

http://dx.doi.org/10.5935/0004-2749.19950079

SUMMARY

This study was performed to demonstrate this increase with two beta-blockers (timolol 0.5% and betaxolol 0.5%) in 21 normal volunteers and 11 glaucomatous patients, and the relationship between flare and IOP variations.

The study was performed before and two hours after the instillation of one drop of timolol on the right eye and one drop of betaxolol on the left eye. The results have shown that for normal volunteers timolol and betaxolol increased significantly the flare in two hours (P < O.05) but the increase was higher with timolol than betaxolol (P < 0.05). In the glaucomatous patients group the flare increase was not significant two hours after medications. When were compared both medications for each group. the timolol increased higher the flare on normal than glaucomatous (P < 0.05) and betaxolol did not show any difference. It was not possible to correlate flare and IOP variations.

Key-words: glaucoma; timolol; betaxolol; aqueous humor

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