Bilateralidade, simetria e correlação clínico-eletrofisiológica na retinose pigmentar

Autores:

Flávio R. L Paranhos,

Márcio B Nehemy,

Tatsuo Hirose

ARTIGO ORIGINAL

Arquivos Brasileiros de Oftalmologia

versão impressa ISSN 0004-2749versão On-line ISSN 1678-2925

Arq. Bras. Oftalmol. vol.61 no.4 São Paulo ago. 1998

http://dx.doi.org/10.5935/0004-2749.19980041

SUMMARY

Purpose:

To study the symmetry of clinical manifestations, as well as the correlation between psychophysical and electrophysiological findings in patients with retinitis pigmentosa (RP).

Methods:

58 (32 male and 26 female) RP patients (mean age = 34.4 ± 16.8 years), 32 men and 26 women, were tested. Visual acuity (VA), Goldmann visual field (VF), electroretinogram (ERG) and electro-oculogram (EOG) were performed. Student's test for dependent samples and Pearson's correlation were performed.

Results:

Mean VA was LogMAR = 0.35 (Snellen equivalent 20/45) for right eye (OD) and LogMAR = 0.37 (Snellen equivalent 20/47) for left eye (OS). Mean VF was 20° for both eyes (OU). Inter-ocular correlation (Pearson's "r" coefficient) was 0.722 (VA; p < O. 05) and 0.967 (VF; p < 0.05). 21 patients had a recordable ERG; the mean amplitude was not significantly different (p > 0.05) between eyes, for any of the ERG components. The mean VF was significantly better in RP patients with a recordable ERG than in the nonrecordable group (approximately 35° and 15°, respectively; p < 0. 05). 16 patients had a recordable EOG (mean ARDEN ratio: 1.41 ± 0.42, OD and 1.57 ± 0.58, OS; p > 0.05).

Conclusion:

A high interocular symmetry of clinical manifestations, as well as a significant correlation between VF and ERG were observed in our RP patients.

Key-words: Retinitis pigmentosa; Bilaterality; Symmetry; Electroretinogram (ERG); Electro-oculogram (EOG

Texto completo disponível apenas em PDF.

REFERÊNCIAS

1 Dantas AM. Eletrorretinograma. In: Dantas AM, Costa JGC, Pacini Neto L, Yamane R, Elias CA. Biblioteca Brasileira de Oftalmologia. Eletrofisiologia Ocular. 1ª ed. Rio de Janeiro: Editora Cultura Médica, 1995: 141-225.

2 Marmor MF, Aguirre G, Arden G et al. Retinitis pigmentosa. A symposium on terrninology and methods of examination. Ophthalmology 1983;90:126-31.

3 Nakanami CR, Farah ME, Martins MC, Takahashi W. Retinose pigmentária associada a toxoplasmose ocular. Arq Bras Oftalmol 1994;57:317-21.

4 Silveira C, Belfort Jr. R, Nussemblatt R, Farah ME, Takahashi W, Imamura P, Burnier Jr. M. Unilateral pigmentary retinopathy associated with ocular toxoplasmosis. Am J Ophthalmol 1989; 107(suppl.6):682-4.

5 Madreperla SA, Palmer RW, Massof RW, Finkelstein D. Visual acuity loss in retinitis pigmentosa. Relationship to visual field loss. Arch Ophthalmol 1990; 108:358-61.

6 Sabates R, Hirose T, Mc Meel JW. Electroretinography in the prognosis and classification of central retina! vein occlusion. Arch Ophthalmol 1983;101:232-5.

7 Matsui Y, Katsumi O, Mehta M, Hirose T. Correlation of electroretinographic and angiographic findings in unilateral central retinal vein obstruction. Graefe's Arch Clin Exp Ophthalmol 1994;232:449-57.

8 Arden GB, Barrada A, Kelsey JH. New clinical test of retina! function based upon the standing potential of the eye. Brit J Ophthalmol 1962;46:449-67.

9 Arden GB, Fojas MR. Electrophysiological abnormalities in pigmentary degenerations of the retina. Assessment of value and basis. Arch Ophthalmol 1962;68: 105-24.

10 Berson EL, Gouras P, Gunkel RD. Rod responses in retinitis pigmentosa, dominantly inherited. Arch Ophthalmol 1968;80:58-67.

11 Tamiozo MA, Rocha HR, Gonçalves ER, Antunes L. ERG e AGS em filhos de pacientes com retinose pigmentar. Arq Bras Oftalmol 1987;50:53-65.

12 Berson EL, Rosner B, Sandberg MA, Hayes KC, Nicholson BW, Weigel-Di-Franco C, Willett W. A randomized trial of vitamin A and vitamin E supplementation for retinitis pigmentosa. Arch Ophthalmol 1993;111:761-72.

13 Marmor MF. Visual loss in retinitis pigmentosa. Am J Ophthalmol 1980;89:692-8.

14 Massof RW, Finkelstein D, Starr SJ, Kenyon K, Fleischman JA, Maumenee IH. Bilateral symmetry of vision disorders in typical retinitis pigmentosa. Brit J Ophthalmol 1979;63:90-6.

15 Ross DF, Fishman GA, Gilbert LD, Anderson RJ. Variability of visual field measurements in normal subjects and patients with retinitis pigmentosa. Arch Ophthalmol 1984;102:1004-10.

16 Sandberg MA, Weigel-DiFranco C, Rosner B, Berson EL. The relationship between visual field size and electroretinogram amplitude in retinitis pigmentosa. Invest Ophthalmol Vis Sci 1996;37:1693-8.

Outros artigos científicos

Autoavaliação Dos Recursos Comunicativos Por Representantes Comerciais e Sua Relação com o Desempenho em Vendas CoDAS

Formação Médica Na Atenção Primária À Saúde: Experiência com Múltiplas Abordagens Nas Práticas de Integração Ensino, Serviço e Comunidade Interface - Comunicação, Saúde, Educação

"Acidente de Dupla Espécie": Uma Terceira Espécie de Acidente Do Trabalho e Sua Importância para a Vigilância em Saúde Do Trabalhador Ciência & Saúde Coletiva

Adaptação Cultural Do Test Of Narrative Language (Tnl) para o Português Brasileiro CoDAS