Estudo da mucosa labial enxertada em bulbo ocular para correção de simbléfaro

Estudo da mucosa labial enxertada em bulbo ocular para correção de simbléfaro


Ana Estela Besteti P. P. Sant'Anna,
Waldir Martins Portellinha,
Moacyr P. Rigueiro,
Paulo Sérgio de Moraes Barros


Arquivos Brasileiros de Oftalmologia

versão impressa ISSN 0004-2749versão On-line ISSN 1678-2925

Arq. Bras. Oftalmol. vol.62 no.2 São Paulo abr. 1999



To evaluate labial mucous membrane graft in patients with severe symblepharon.


Ten patients were operated for labial mucous membrane graft. Mean age was 47.2 years (range 26-68 years). Symblepharons were caused by trauma, Stevens-Johnson syndrome, recidivous pterygium and cicatricial chronic conjunctivitis.


The grafts were biopsied after cicatrization. All patients presented nonkeratinizing stratified columnar epithelium without metaplasia.


Labial mucous membrane grafting has good results in the treatment of patients with severe symblepharon. The mucous membrane does not change its natural histologic aspects when grafted on ocular surface.

Keywords: Labial mucous membrane graft; Symblepharon; Mucous membrane


1 Denig R. Circumcomeal transplantation of buccal mucous membrane as a curative measure in diseases of the eye. Arch Ophthalmol 1929;1:351-7.
2 Denig R. The indications for immediate transplantation of buccal mucous membrane for eye bums. Med Record 1938;148:395-9.
3 O'Connor GB. Early grafting in burns of the eye. Arch Ophthalmol 1933;9:48-51.
4 Brown AL. Lime bums ofthe eye: Use ofrabbit peritoneum to prevent severe delayed effects: Experimental studies and report of a case. Arch Ophthalmol 1941;26:754-69.
5 Siegel R. Buccal mucous membrane grafts in treatment of burns of the eye. Arch Ophthalmol 1944;32:104-8.
6 Ballen PH. Mucous membrane grafts in chemical (lye) burns. Am J Ophthalmol 1963;55:302-12.
7 Shore J, Foster S, Westfall C, Rubin P. Results of Buccal Mucosal Grafting for Patients with Medically Controlled Ocular Cicatricial Pemphigoid. Ophthalmology 1992;99:383-95.
8 Kenyon KR, Wagoner MD, Hettinger ME. Conjunctival autograft Transplantation for Advanced and Recurrent Pterygium. Ophthalmology 1985;92:1461-70.
9 Kwitko S, Marinho D, Barcaro S, Bocaccio F, Rymer S, Fernandes S, Neumann J. Allograft conjunctival transplantation for bilateral ocular surface disorders. Ophthalmology 1995;102:1020-5.
10 Neuhaus RW, Baylis HI, Shorr N. Complications at mucous membrane donor sites. Am J Ophthalmol 1982;93:643-6.