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Estudo da variação do conteúdo protéico do humor aquoso após instilação de colírio de pilocarpina, timolol e betaxolol avaliado pela laser flare fotometria

Estudo da variação do conteúdo protéico do humor aquoso após instilação de colírio de pilocarpina, timolol e betaxolol avaliado pela laser flare fotometria

Autores:

Mirian Skaf,
Paulo Augusto de Arruda Mello,
José Carlos Reys,
Cristina Muccioli,
Rubens Belfort Jr.

ARTIGO ORIGINAL

Arquivos Brasileiros de Oftalmologia

versão impressa ISSN 0004-2749versão On-line ISSN 1678-2925

Arq. Bras. Oftalmol. vol.57 no.1 São Paulo fev. 1994

http://dx.doi.org/10.5935/0004-2749.19940077

SUMMARY

The flare variation was studied before and 2 hours after the instillation of 1 drop of 0.5% timolol, 2% pilocarpine or 0.5% betaxolol in 26 normal volunteers by laser flare photometry. Pilocarpine and timolol increased the flare measurements in the average of 143.7% and 81.6% above the baseline readings respectively for the first group studied (6 patients, 12 eyes). The difference was statiscally significant (P<0.05).

Timolol increased the flare in 78.2% and betaxolol increased it in 33.2% above the baseline, in average, for the second group studied (20 subjects, 40 eyes).

Betaxolol induced a significant smaller increase of the flare measurements when compared to timolol and pilocarpine (P<0,01).

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