Indicações de transplante penetrante de córnea. 1991-1995

Indicações de transplante penetrante de córnea. 1991-1995


Maria Cristina Nishiwaki-Dantas,
Paulo Elias Correa Dantas,
Nilo Holzchuh,
Adamo Lui Netto,
Renato Giovedi Filho,
Marizilda Giovedi,
Geraldo Vicente de Almeida


Arquivos Brasileiros de Oftalmologia

versão impressa ISSN 0004-2749versão On-line ISSN 1678-2925

Arq. Bras. Oftalmol. vol.61 no.1 São Paulo fev. 1998


Charts of patients who had undergone penetrating keratoplasty at Hospital da Santa Casa de São Paulo, from January 1991 to December 1995 were retrospectively reviewed, regarding the leading indications. There were 249 keratoplasties in this 5-year in terval.

The average age of patients was 42. 6 years (range 1 to 89 years). Nineteen corneal transplants (7. 6%) were performed in children ≤ 12 years old.

The cases were distributed among 1 6 diagnostic categories, according to Lindquist.

The most common indication was keratoconus accounting for 21.7% of cases, contrasting with other studies which have found pseudo-phakik bullous keratopathy to be the leading indication with gradual decrease of keratoconus. On the other h a n d, pseudo-phakik bullous keratopathy was the fifth most common indication accounting for only 5% of the cases.

Regraft was the second most frequent indication . Trauma and ulcerative conditions with or without infection that are com m only associated to corneal inflammation and vascularization were more prevalent among the regrafts.

Infeccious and post infeccious keratitis were the third indication, followed by trauma. Among corneal dystrophies, Fuchs was the most frequent (3.6%). Other dystrophies constituted a small, but important group of disorders (6.4%o), mainly macular dystrophy. Fifteen cases (6%) were viral keratitis, 9 for herpes (simplex and zoster).


1 Arentsen JJ, Morgan B, Green R. Changing indications for keratoplasty. Am J Ophthalmol 1976;81:313-8.
2 Smith RE, McDonald HR, Nesburn AB, Minckler DS. Penetrating keratoplasty. Changing indications, 194 7-1978. Arch Ophthalmol 1980;98: 1226-9.
3 Robin JB, Gindi JJ, Koh K, cols. An update of the indications for penetrating keratoplasty - 1979 through 1983. Arch Ophthalmol 1986;104:87-9.
4 Mohamadi P, Me Donnell JM, Irvine JA & cols. Changing indication for penetrating keratoplasty - 1984-1988. Am J Ophthalmol 1989;107:550-2.
5 Mamalis N, Anderson CW, Kreisler KR & cols. Changing trends in the indications for penetrating keratoplasty. Arch Ophthalmol 1992;110:1409-11.
6 Morris R J, Bates AK. Changing indications for keratoplasty. Eye1989;3:455-9.
7 Kervick GN & Shepherd WFI. Changing indications for penetrating keratoplasty. Ophthalmic Surg 1990;21:227.
8 Lindquist TD, Me Glothan JS, Rotkis WM, Chandler JW. Indications for penetrating keratoplasty: 1980-1988. Cornea 1991 ; 10:210-6.
9 Shariff KW, Casey TA. Changing indications for penetrating keratoplasty. Eye 1983;7:485-8.
10 Brady SE, Rapuano CJ, Arentsen JJ & cols. Clinical indications for and procedures associated with penetrating keratoplasty, 1983-1988. Am J Ophthalmol 1989;108:118-22.
11 Damji KF; Rootman J, White VA & cols. Changing indications for penetrating keratoplasty in Vancouver, 1978-87. Can J Ophthalmol 1990;25:243-8.
12 Hyman L, Wittpenn J, Yang C. Indications and techniques of penetrating keratoplasties, 1985-1988. Comea 1992; 11:573-6.
13 Lindquist TD, Me Neill JJ, Wilhelmus KR. Indications for keratoploasty. Cornea 1994;13:105-7.
14 Rapuano CJ, Cohen EJ, Brady SE & cols. Indications for and outcomes of repeat penetrating keratoplasty. Am J Ophthalmol 1990; 109:689-95.
15 Mac Ewen CJ, Han Zuh, Anderson E, Mac Ewen CG. Corneal re-graft: indications and outcome. Ophthalmic Surg 1988;19:706-12.
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