O valor da análise bioquímica de Staphylococcus aureus na determinação da sensibilidade à eritromicina

O valor da análise bioquímica de Staphylococcus aureus na determinação da sensibilidade à eritromicina


Alexandre S. Marcon,
Giovanni M. Travi,
Italo M. Marcon,
Zélia M. Corrêa


Arquivos Brasileiros de Oftalmologia

versão impressa ISSN 0004-2749versão On-line ISSN 1678-2925

Arq. Bras. Oftalmol. vol.62 no.2 São Paulo abr. 1999



To assess the reliability of biochemical pattern (biotype) to determine erythromycin sensitivity of multiple Staphylococcus aureus isolates from the conjunctiva and lid margin of healthy eyes.


The authors analyzed 42 samples of S. aureus, isolated from 100 volunteers, through MicroScan® (Dade lnternational, West Sacramento, CA) Pos-Combo type 6 panels. Biochemical reactions were organized in a table. The biotype number was determined by adding values of each reaction according to the manufacturer's instructions.


Biotype 317147 was more prevalent (n = 19), 11 being sensitive to erythromycin and 8 resistant. Other biotypes were analyzed: 317163 (n = 8), 317167 (n = 6), 317347 (n = 2), etc.


It was concluded that biotyping alone can not predict everythromycin sensitivity erythromycin sensibility for S. aureus biotype 317147 (CI 95%o, 0.29-0.087 for sensible isolates and 0.08-0.76 for resistant isolates).

Keywords: Staphylococcus aureus; MicroScan; Erythromycin; Biotyping


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