Oftalmia simpática grave: relato de caso

Oftalmia simpática grave: relato de caso


José Alvaro Pereira Gomes,
Ronaldo Barcellos,
Fernando Crosta,
Erlan Stephen de Marco,
Maria Auxiliadora Sibinelli,
José Vital Filho,
Carlos Roberto Neufeld


Arquivos Brasileiros de Oftalmologia

versão impressa ISSN 0004-2749versão On-line ISSN 1678-2925

Arq. Bras. Oftalmol. vol.62 no.3 São Paulo jun. 1999



The authors present a case of severe sympathetic post-phacoemulsification ophthalmia which was treated with systemic immunosuppression and enucleation of the sympathizing eye. The patient presented resolution of the inflammatory picture and improvement in visual acuity. The clinical characteristics, diagnosis, pathophysiology and therapeutic aspects of sympathetic ophthalmia are discussed.

Keywords: Uveitis; Sympathetic ophthalmia; Enucleation; Immunosuppression


1 Liddy N and Stuart J. Sympathetic ophthalmia in Canada. Can Ophthalmol 1972;7:157-9.
2 Albert DM and Diaz-Rohena R. A historical review of sympathet c ophthalmia and its epidemiology. Surv Ophthalmol 1989;34:1-14.
3 Jennings T and Tessler HH. Twenty cases of sympathetic oph:halmia. Br J Ophthalmol 1989;73: 140-5.
4 Chan CC, Roberge FG, Whitcup SM, Nussenblatt RB. 32 Cases of Sympathetic ophthalmia. Arch Ophthalmol 1995; 113:597-600.
5 Jakobiec FA, Marboe CC, Knowles II DM, lwamoto T, Harrison W, Chang S, Coleman J. Human sympathetic ophthalmia: an analysis of the nflammatory infiltrate by hybridoma-monoclonal antibodies, imunochemistry, and correlative eletron microscopy. Ophthalmology 1983;90:76-95.
6 Chan CC, Palestine AG, Nussenblatt RB, Roberge FG, Benezra D. Antiretinal autoantibodies in Vogt-Koyanagi-Harada syndrome, Behçet's disease, and sympathetic ophthalmia. Ophthalmology 1985;92: 1025-8.
7 Power WJ & Foster CS. Update on sympathetic ophthalmia. Inl Ophthalmol Clin 1995;35:127-37.
8 Pereira MB & Pereira CM. Oftamia simpática após traumatismo ocular contuso. Rev Bras Oftalmol 1996;55:35-40.
9 Lubin JR, Albert DM, Weinstein M. Sixty fiveyears of sympathetc ophthalmia: a clinicopathological review of 105 cases (1913-1978). Ophthalmology 1980;87:109-21.
10 Wong VG, Anderson R, O'Brien PJ. Sympathetic ophthalmia and lymphocyte transforrnation. Am J Ophthalmol 1971;72:960-5.
11 Gomes JAP, Rizzo LV, Nishi M, Donoso LA, Dua HS. Influência do epitélio corneal limbar sobre a expressão do antígeno dos linfócitos da mncosa humana (Hml-1). Arq Bras Oftalmol 1997;60:588-97.
12 Kim MK & Belfort Jr R. Uveíte facogênica. In: Oréfice F & Belfort Jr R, eds. Uveítes. São Paulo: Livraria Roca Ltda., 1987;310.
13 Reynard M, Schulman IA, Azen SP, Minckler D. Histocompatibility antigens in sympathetic ophthalmia. Am J Ophthalmol 1983;95:216-21.
14 Dick AD, Azim M, Forrester JV. Immunosuppressive therapr for chronic uveitis: optimising therapy with steroids and cyclosporin A. Br J Ophthalmol 1997;81:1107-12.