Compartilhar

Transplante de córnea em aniridia: relato de dois casos

Transplante de córnea em aniridia: relato de dois casos

Autores:

João Roberto Schneider,
Luciana Nerung,
Diane Marinho,
Sérgio Kwitko

ARTIGO ORIGINAL

Arquivos Brasileiros de Oftalmologia

versão impressa ISSN 0004-2749versão On-line ISSN 1678-2925

Arq. Bras. Oftalmol. vol.58 no.5 São Paulo out. 1995

http://dx.doi.org/10.5935/0004-2749.19950030

SUMMARY

Visual impairment due to important corneal opacity in aniridia is not common, and there are very few reports of corneal transplantation in this condition. We report two cases of penetrating keratoplasty in two patients with familiai aniridia, discussing the technique of the procedure. One patient had also associated Peters anomaly and congenital rubella, and the other cataract and congenital syphilis, findings that are discussed. Significative improvement in visual acuity were achieved in both cases, during a follow-up period of 32 months. Persistent epithelial defect, vortex (whorl) keratopathy, two episodes of allograft rejection and glaucoma were the post-operative complications that occured in one patient and were clinically controlled.

REFERÊNCIAS

1 BEUCHAMP, G. R. - Anterior segment dysgenesis, keratolenticular adhesion and aniridia. J. Pediatr. Ophthalmol. and Strabismus, 17: 55-8, 1980.
2 Apud: BENTIJANE, A. J. e BECHARA, J. S. - Aniridia. In: ALMEIDA, H. G. (ed.): Glaucomas secundários. São Paulo, Roca 1989. cap. 3, pag. 23-27.
3 GRAYSON, M. - Anomalías congênitas. In: GRAYSON, M. - Enfermedades de la córnea. Bogotá, Panamericana, 1985. cap. 3, pag. 36-37.
4 KENYON, K. R.; FOGLE, J. A.; GRAYSON, M. - Dysgenesis, dystrophies and degenerations of the cornea. In: DUANE, T. D. (ed): Clinical Ophthalmology. Philadelphia, Harper and Row Publishers, 1987. vol. 4, cap. 16, pag. 7-9.
5 KIVLIN, J. D.; FINEMAN, R. M.; CRANDALL, A. S., et al - Peters’ anomaly as a consequence of genetic and nongenetic syndromes. Arch. Ophthalmol., 104: 61-64, 1986.
6 KREMER, I.; KAJPAL, R. K.; RAPUANO, C. J.; et al - Results of penetrating keratoplasty in aniridia. Am. J. Ophthalmol., 115: 317-320, 1993.
7 MINTZ-HITNER, H. A.; FERREL, R. E.; LYONS, L. A., et al - Criteria to detect minimal expressivity within families with autossomal dominant aniridia. Am. J. Ophthalmol., 114: 700-707, 1992.
8 SCHANZLIN, D. J.; GOLDBERG, D. B.; BROWN, S. I. - Hallerman-Streiff syndrome associated with sclerocornea, aniridia and a chromosomal abnormality. Am. J. Ophthalmol., 90: 411-415, 1980.
9 SCHIELDS, M. B. - Developmental glaucomas with associated anomalies. In: SCHIELDS, M. B. (ed): Textbook of Glaucoma. Baltimore, Williams and Wilkins, 1992. 3a. ed. cap. 12, pp. 245-252.
10 WEINER, M. J.; ALBERT, D. M. - Congenital corneal keloid. Acta Ophthalmol (suppl), 192: 188-96, 1989.