Compartilhar

Uso da Colagel® na cirurgia da conjuntiva - estudo experimental

Uso da Colagel® na cirurgia da conjuntiva - estudo experimental

Autores:

Cláudio Asperti Spera,
Silvana Artioli Schellini,
Maria Rosa Bet de Moraes Silva,
Mariângela Esther Alencar Marques,
Sheila Canavese Rahal

ARTIGO ORIGINAL

Arquivos Brasileiros de Oftalmologia

versão impressa ISSN 0004-2749versão On-line ISSN 1678-2925

Arq. Bras. Oftalmol. vol.61 no.2 São Paulo abr. 1998

http://dx.doi.org/10.5935/0004-2749.19980072

SUMMARY

The authors studied the ocular tissue reactions produced by the application of the tissue adhesive Colagel® (Cirumédica), with the aim of evaluating the possibility of its accomplishment in the pterigium surgery with the technique of conjunctival transplant. Twelve rabbits were submitted to limbic peritomy with Colagel application on the sclera, being covered by conjunctive. Three animals were not opperated and composed the control group. The animals in the dates 3, 7, 15 and 30 days after surgery were killed. The orbit was exenterated and the material prepared for hystologic exam. Since the first days of postoperative, intense inflammatory reaction was observed in the place of inoculation of the adhesive, as inner the eye. With the evolution, there was an apparent improvement of the inflammation, with limitation of the reaction to the inoculation place; even thought, the intra-ocular inflammation (iritis, vitreitis, coroiditis) continued with necrosis and perforation near the inoculation place. lt can be ended that the Colagel® is not rendered to use in conjunctival surgeries.

Key words: Tissue adhesive; Conjunctival transplant; Pterigium

REFERÊNCIAS

1 Flament J, Speeg-Schatz V, Weber M. Etat actuel du traitement du ptérygion. J Fr Ophtalmol 1993;16:401-10.
2 Gentile G, Formelli G, Morrone GF et al. A cola de fibrina humana na microcirurgia experimental. Arq Bras Med 1993;67:365-7.
3 Bonati JA, Tolosa EMC, Matheus LCA et al. Cola de fibrina em perfuração corneana experimental em cão. Arq Bras Oftalmol 1995;58:88-92.
4 Grupenmacher F, Adib FC. Estudo experimental do colagel: novo adesivo biológico em córnea de coelho. An Oftalmol 1990;9:46-50.
5 Lee KH, Kim MS, Hahn TW, Kim JH. Comparison of histologic findings in wound of rabbit scleral homografts with fibrin glue (Tissell®) and suture material. J Refract Surg 1995;11:397-401.
6 Ramos ARB, Torres LFB, Moreira Jr CA, Costa PB, Matsumoto LH. Uso do adesivo biológico de fibrina no tratamento do descolamento de retina regmatogênico experimental em coelhos: estudo histopatológico. Arq Bras Oftalmol 1996;59:137-46.
7 Peyret JA. Uso del fibrinógeno humano concentrado en el cierre de heridas quirúrgicas oculares en el conejo. Arch Oftalmol (Buenos Aires) 1996;61:33-6.
8 Morandini W, Ortiz V. Adesivos biológicos em cirurgia. Acta Cirurg 1992;7:80-5.
9 Laus JL, Morales A, Ferreira A L et al. Avaliação comparativa dos efeitos de um novo adesivo biologógico (Colagel®) sobre a resistência tênsil e a cicatrização de anastomoses intestinais. Trabalho experimental em cães. Braz J Vet Res Anim Sci 1992;29:83-91.